Brain metastasis of lung cancer
Conditions
Interventions
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Proactively collect biological samples and clinical information from patients with brain metastases Inclusion criteria Among the brain tumor patients admitted to the Department of Neurosurgery at Huashan Hospital affiliated to Fudan University, those who meet the following criteria can be enrolled: 1) Aged over 18, with no gender restrictions; 2) Preoperative imaging suspected lung cancer with brain metastasis; 3) Requires surgery; 4) The intraoperative frozen section pathology report revealed a brain metastasis of lung cancer; 5) A certain amount of fresh biological samples can be taken for research on the basis of ensuring that it does not affect the needs of clinical routine diagnosis and treatment; 6) Voluntarily sign the informed consent form. Retrospectively collect biological samples and clinical information from primary and metastatic foci of brain metastases in lung cancer Inclusion criteria Among the cases of lung cancer with brain metastasis diagnosed by the Department of Pathology at Huashan Hospital affiliated to Fudan University, all those who meet the following criteria can be enrolled: 1) Aged over 18, with no gender restrictions; 2) Pathological diagnosis of lung cancer with brain metastasis and paraffin samples of the primary lesion; 3) On the basis of ensuring that it does not affect clinical routine diagnosis, paraffin sections (5 slices) can be taken for immunohistochemical staining; 4) The patient voluntarily joins this study.
Exclusion criteria
Exclusion criteria: Proactively collect biological samples and clinical information from patients with brain metastases Exclusion criteria Patients who meet any of the following criteria will not be eligible for enrollment in this study: 1) The intraoperative frozen section pathology report does not indicate brain metastasis of lung cancer; 2) After excluding the samples required for normal diagnosis and treatment, the remaining sample size is insufficient for research; 3) The patient is unwilling to participate in the study. Retrospectively collect biological samples and clinical information from primary and metastatic foci of brain metastases in lung cancer Exclusion criteria Patients who meet any of the following criteria will not be eligible for enrollment in this study: 1) Wax blocks that have been stored for too long and have become moldy; 2) Those who are unwilling to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| genome sequencing;RNA sequencing; | — |
Countries
China
Contacts
Public ContactYu Yao
Huashan Hospital, Fudan University
Outcome results
None listed