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Efficacy Evaluation of Acupuncture and Moxibustion for Post-Stroke Aphasia and Its Brain Plasticity Mechanism Based on Functional Magnetic Resonance Imaging Studies

Efficacy Evaluation of Acupuncture and Moxibustion for Post-Stroke Aphasia and Its Brain Plasticity Mechanism Based on Functional Magnetic Resonance Imaging Studies

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114452
Enrollment
Unknown
Registered
2025-12-11
Start date
2025-12-11
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke Aphasia

Interventions

Acupuncture-Moxibustion Therapy Group:The acupuncture-moxibustion therapy group received scalp acupuncture (bilateral temporal area) with dense needle insertion, retaining the needles for 6 hours. Aft
Control Group:The acupuncture-moxibustion therapy group received scalp acupuncture (dense needle insertion) in the right temporal region, retaining the needles for 30 minutes, followed by 30 minutes o

Sponsors

Huai'an Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with stroke confirmed by brain CT or MRI, with lesions in the left cerebral hemisphere; 2. First episode, single lesion, disease duration between 15 and 30 days, able to sit independently in a wheelchair for 1 hour; 3. Non-fluent aphasia diagnosed according to the Western Aphasia Battery (WAB) criteria: Aphasia Quotient (AQ) < 93.8, speech fluency score 0–4; 4. Native Chinese speakers; 5. Primary school education or above; 6. No epilepsy or severe somatic diseases; 7. Right-handed; 8. Conscious and cooperative; 9. Patients and their families have signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with pre-existing language disorders prior to the current episode or those with severe dysarthria complicating the current condition; 2. Patients with concurrent neurodegenerative diseases (e.g., dementia, Parkinson's disease, motor neuron disease) causing speech disorders; 3. Patients with epilepsy or other severe somatic diseases; 4. Patients with visual, auditory, or cognitive impairments affecting language assessment and treatment; 5. Patients with metallic foreign bodies or other implanted electronic devices.

Design outcomes

Primary

MeasureTime frame
Western Aphasia Battery (WAB);Functional Magnetic Resonance Imaging (fMRI) Brain Function Index;Boston Naming Test;Retelling Tasks;

Countries

China

Contacts

Public ContactLi Xuejing

The Second Affiliated Huai'an Hospital of Xuzhou Medical University

lixuejing914@163.com+86 139 1510 3901

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026