Thrombotic microangiopathy
Conditions
Interventions
Children's Thrombotic Microangiopathy:None
Sponsors
Beijing Children's Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: From December 2015 to January 2025, a retrospective analysis was performed on children who were first diagnosed with TMA at Beijing Children's Hospital affiliated to Capital Medical University. Inclusion Criteria: (1) Met the clinical diagnosis of TMA; (2) Age< 18 years old. Diagnostic criteria for TMA include: (1) microangiopathic hemolytic anemia (hemoglobin < 100 g/L, elevated lactate dehydrogenase, and broken red blood cells on peripheral blood smear); (2) thrombocytopenia (platelet count < 150×109/L); (3) Organ damage.
Exclusion criteria
Exclusion criteria: (1) Children with a history of TMA; (2) Children who have been treated in other hospitals for more than 4 weeks; (3) Children with missing data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival or Death;End-stage kidney disease;Basic Information;Initial clinical manifestations at disease onset.;Lactate dehydrogenase;Urea;Blood complement levels;Medication regimen (drug types);Clinical routine examination data at the final hospitalization or outpatient follow-up; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin;Platelet;Blood creatinine; | — |
Countries
china
Contacts
Public ContactChenguang Jia
Beijing Children's Hospital, Capital Medical University
Outcome results
None listed