Major depressive disorder
Conditions
Interventions
Sponsors
Wuxi Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the MDD group: 1.Meeting the diagnostic criteria for Major Depressive Disorder (MDD) as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); 2.Age 18-55 years old; 3.Participants had no history of substance abuse or dependence, and an absence of suicidal ideation or behaviors. 4.Wth no significant medical conditions. HC Group Inclusion Criteria: 1. Age, gender, and years of education matched with the MDD group; 2. No history of mental illness, epilepsy, or brain injury.
Exclusion criteria
Exclusion criteria: MDD group 1.Individuals meeting the DSM-5 diagnostic criteria for schizophrenia, dementia, bipolar disorder, or other cognitive disorders. 2.Individuals with a history of cerebrovascular disease, other neurological disorders, or significant systemic medical conditions. 3.Individuals with a history of alcohol or other substance use disorders. 4.Individuals who have undergone Modified Electroconvulsive Therapy (MECT) within the past 6 months. HC Group 1. Suffering from major physical illnesses or medical history of severe heart, brain, kidney, endocrine diseases, etc.; 2. Having family members diagnosed with mental illnesses such as depression, bipolar disorder, or schizophrenia; 3. Currently having serious suicide attempts or severe agitation and excitement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Event-Related Potential (ERP);Emotional Face Recognition Task / Emotional Faces Paradigm;2-Back Task (a working memory paradigm);Monetary Incentive Delay (MID) Task;Continuous Performance (CPT);Interoception; | — |
Countries
China
Contacts
Public ContactTiantian Wang
Wuxi Mental Health Center
Outcome results
None listed