Primary Lung Cancer and Recurrent/Metastatic Lung Cancer
Conditions
Interventions
Pathological Type Transformation Group
:none
Pathological Type Non-Transformation Group.:none
Sponsors
Huadong Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients with histopathologically confirmed primary lung cancer according to the WHO 2021 classification criteria; 2.Presence of recurrent or metastatic lesions with pathological confirmation of the lesions; 3.Pathological information definitively characterized by immunohistochemistry (IHC);
Exclusion criteria
Exclusion criteria: 1.Personal history of other malignancies; 2.Patients with synchronous multiple primary lung cancers (confirmed by histopathological and molecular criteria per IASLC guidelines); 3.Pathological specimens indeterminate for histological classification after comprehensive IHC/NGS analysis; 4.Cases with ambiguous origin (primary vs. metastatic) despite multidisciplinary review; 5.Other conditions contraindicating study participation as assessed by investigators;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histological Transformation Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in pathological information between primary and recurrent metastatic lesions.;Conversion of pathological types under different therapeutic pressures.;Overall survival time and progression-free survival time.; | — |
Countries
China
Contacts
Public ContactZheng Li
Huadong Hospital
Outcome results
None listed