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Association between Ocular Surface Microenvironment and Retinal Microvascular Network in Patients with Rheumatoid Arthritis

Association between Ocular Surface Microenvironment and Retinal Microvascular Network in Patients with Rheumatoid Arthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114394
Enrollment
Unknown
Registered
2025-12-11
Start date
2025-12-31
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Interventions

Group RA: Patients with Rheumatoid Arthritis

Sponsors

Eye Hospital, The First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18–75 years, both genders; 2. meeting the 2010 ACR/EULAR classification criteria for rheumatoid arthritis; 3.voluntarily participating in this study and signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Diagnosis of other autoimmune diseases or a family history thereof; 2.Presence of systemic diseases affecting the cornea, such as diabetes mellitus; 3.Corneal diseases, such as corneal dystrophy, keratitis, keratoconus, etc.; 4.History of uveitis; 5.History of ocular trauma; 6.History of contact lens wear; 7.History of corneal surgery; 8.Use of topical ophthalmic antibiotics, corticosteroids, or immunosuppressants within the preceding 4 weeks; 9.Other conditions deemed unsuitable for participation by the investigators.

Design outcomes

Primary

MeasureTime frame
Microspots in the corneal stroma;Conjunctival sac microbiota;corneal nerve;

Countries

China

Contacts

Public ContactXin Jin

Eye Hospital, The First Affiliated Hospital of Harbin Medical University

zdshjinxinbisheng@163.com+86 158 4662 2927

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026