Rheumatoid Arthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 18–75 years, both genders; 2. meeting the 2010 ACR/EULAR classification criteria for rheumatoid arthritis; 3.voluntarily participating in this study and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Diagnosis of other autoimmune diseases or a family history thereof; 2.Presence of systemic diseases affecting the cornea, such as diabetes mellitus; 3.Corneal diseases, such as corneal dystrophy, keratitis, keratoconus, etc.; 4.History of uveitis; 5.History of ocular trauma; 6.History of contact lens wear; 7.History of corneal surgery; 8.Use of topical ophthalmic antibiotics, corticosteroids, or immunosuppressants within the preceding 4 weeks; 9.Other conditions deemed unsuitable for participation by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microspots in the corneal stroma;Conjunctival sac microbiota;corneal nerve; | — |
Countries
China
Contacts
Eye Hospital, The First Affiliated Hospital of Harbin Medical University