High-risk infants
Conditions
Interventions
Gold Standard:The Gesell Developmental Scale (GDS) comprises five domains: Adaptive Behavior, Social Behavior, Language, Gross Motor, and Fine Motor. DQ score of less than 75 is defined as development
Index test:Multiparametric MRI Feature Analysis
Sponsors
Wuxi Children's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Clinically diagnosed as high-risk infants; 2. For corrected gestational age <45 weeks, undergo routine cranial MRI examination; 3. Complete at least one standardized neurodevelopmental follow-up assessment.
Exclusion criteria
Exclusion criteria: 1. Missing Gesell scale; 2. Incomplete perinatal clinical data; 3. Poor MRI image quality or major intracranial structural lesions; 4. Repeated multiple examinations; 5. Failure in image segmentation or feature extraction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity, specificity, accuracy, receiver operating characteristic curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Volume of gray matter and volume of cerebrospinal fluid;Cortical surface area;T1/T2 value of gray matter and T1/T2 value of white matter; | — |
Countries
China
Contacts
Public ContactHaoxiang Jiang
Wuxi Children's Hospital
Outcome results
None listed