Non alcoholic fatty liver disease
Conditions
Interventions
Gold Standard:Histopathological fibrosis staging (according to METAVIR or Brunt criteria) is used as the primary reference standard. In the absence of biopsy results, magnetic resonance elastography (
Index test:AI-driven Liver MRI Foundation Model based on self-supervised learning and multimodal fusion of conventional MRI sequences (T2WI, DWI/ADC, PDFF, R2*), producing patient-level fibrosis stage
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Patients who have completed routine MRI examinations of the upper abdomen or liver for various reasons; 3. Good image quality with clearly distinguishable liver structures; 4. No obvious artifacts or severe lesions affecting image interpretation.
Exclusion criteria
Exclusion criteria: 1. Patients with intrahepatic space-occupying lesions (tumors, cysts, etc.) or severe biliary diseases; 2. Conditions that seriously affect MRI signals, such as obstructive jaundice, acute hepatitis, or significant iron deposition; 3. Patients with incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area Under the Receiver Operating Characteristic curve ;sensitivity;Specificity;Accuracy;F1-score; | — |
Countries
China
Contacts
Public ContactXiao Liang
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed