Skip to content

Development and Validation of a Radiomics Model for Preoperative Risk Prediction in Pancreatic Neuroendocrine Tumors Based on Contrast-Enhanced CT

Development and Validation of a Radiomics Model for Preoperative Risk Prediction in Pancreatic Neuroendocrine Tumors Based on Contrast-Enhanced CT

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114376
Enrollment
Unknown
Registered
2025-12-11
Start date
2025-12-12
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic neuroendocrine tumors

Interventions

Gold Standard:The previously established subtyping criteria for pancreatic neuroendocrine tumors based on sequencing results, DAXX/ATRX mutation status, and tumor size.
Index test:Preoperative enhanced CT imaging analysis (including traditional imaging feature assessment and radiomics analysis)

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Part One: 1. Surgical pathology confirmed a solitary pancreatic neuroendocrine tumor; 2. There are records of classification into indolent and non-indolent neuroendocrine tumors; 3. Preoperative enhanced CT examination was performed; Part Two: Patients with pancreatic neuroendocrine tumors who underwent surgical treatment or did not undergo surgery but have imaging follow-up records for more than 6 months.

Exclusion criteria

Exclusion criteria: Part One 1. Preoperative non-contrast CT examination; 2. Lesions are not visible on contrast-enhanced CT images or there are image quality issues. Part Two 1. No contrast-enhanced CT images available for analysis; 2. Lesions are not visible on contrast-enhanced CT images or image quality does not meet analysis requirements; 3. Patients who have not undergone surgical treatment with a follow-up period of less than 6 months.

Design outcomes

Primary

MeasureTime frame
CT attenuation values of the lesion in the arterial phase;tumor size;CT attenuation values of the pancreatic parenchyma in the arterial phase;CT attenuation values of the lesion in the unenhanced phase;CT attenuation values pancreatic parenchyma in the portal venous phase;CT attenuation values of the lesion in the portal phase;

Countries

China

Contacts

Public ContactHuadan Xue

Peking Union Medical College Hospital

bjdanna95@hotmail.com+86 10 69155509

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026