Postoperative
Conditions
Interventions
control group:The control group received a 20ml adductor canal block under ultrasound guidance with 0.4% ropivacaine after surgery
Experimental Group:The experimental group was administered the 'cocktail' formula + 0.4% ropivacaine 20 ml for muscle relaxation and block under ultrasound guidance.
Sponsors
Ordos Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Stage IV knee osteoarthritis, first-time total knee arthroplasty;The American Society of Anesthesiologists (ASA) physical status classification was I–II; age >=60 years; without severe dysfunction of major organs such as heart, lung, liver, or kidney; patients who voluntarily participated in the study with informed consent.
Exclusion criteria
Exclusion criteria: Patients undergoing bilateral knee replacement; those with other diseases affecting walking ability such as myasthenia gravis; patients undergoing knee revision surgery, malignant tumors, or other diseases; severe systemic diseases such as severe hypertension (crisis), severe diabetes (ketosis, acidosis), coronary heart disease, Chronic Obstructive Pulmonary Disease, asthma, respiratory failure, severe arrhythmias (e.g., atrial fibrillation), second-degree or higher atrioventricular block, sick sinus syndrome, severe valvular heart disease, heart failure, renal failure, stroke or myocardial infarction within the past 6 months, Alzheimer's disease, Parkinson's disease, etc.; patients with mental illnesses or communication disorders; those with a history of chronic pain or allergic reactions to multiple medications; individuals with a history of alcohol abuse or drug addiction; those allergic to opioid drugs; patients with abnormal coagulation function; and those who refuse or are unable to cooperate with the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative resting pain scores at 6, 12, 24, and 48 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. postoperative pain scores during activity at 6, 12, 24, and 48 hours;; 2. muscle strength assessment at 6, 12, 24, and 48 hours; ;3. preoperative and postoperative 24-hour anxiety and depression scores; ;4. postoperative nausea and vomiting incidence within 48 hours.; | — |
Countries
China
Contacts
Public ContactJing xin
Ordos Central Hospital
Outcome results
None listed