Patients with diaphragmatic atrophy following weaning from mechanical ventilation in the ICU
Conditions
Interventions
Respiratory muscle training group:Respiratory muscle training
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Received mechanical ventilation for >=48 hours and successfully weaned off the ventilator; 2. On the day of extubation, three bedside ultrasound measurements of diaphragmatic parameters were taken, with end-expiratory diaphragmatic thickness <=2mm. 3. Voluntary participation in this study requires the patient or their family to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. A history of severe cardiopulmonary disease (e.g., New York Heart Association (NYHA) functional class = III or chronic obstructive pulmonary disease (COPD) GOLD stage >= 3); 2. History of neuromuscular disease; 3. Severe obesity (defined as a body mass index [BMI] greater than 35); 4. Pregnancy; 5. The clinical prognosis was deemed insignificant, and the decision to forgo life-sustaining treatment was documented.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragmatic thickening fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dynamic changes in diaphragmatic thickening scores;ICU length of stay;Intervention compliance and safety indicators;Daily Diaphragm Function and Grip Strength Indicators; | — |
Countries
China
Contacts
Public ContactLan Chen
Shanghai General Hospital
Outcome results
None listed