Abnormal lipid metabolism during pregnancy and pregnancy-related sleep disorders
Conditions
Interventions
Normal sleep quality group:NA
Poor sleep quality group:NA
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Singleton pregnancy, with gestational age of 10–14 weeks at enrollment (confirmed by ultrasound or last menstrual period); 2. Age between 18 and 45 years; 3. Planning to receive prenatal care and deliver at the study center, and able to complete follow-up visits; 4. Able to accept and cooperate with sleep assessments (PSQI questionnaire); 5. Provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe systemic diseases, including active hepatic or renal insufficiency, heart failure, malignant tumors, systemic lupus erythematosus, or other major systemic disorders; 2. Night-shift workers whose circadian rhythm assessment would be significantly affected; 3. Long-term use of medications that affect sleep and cannot be discontinued in the short term (e.g., benzodiazepines, prescription hypnotics, antipsychotic medications); 4. Individuals with a family history of familial hyperlipidemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal lipid profile during pregnancy (TC, TG, HDL-C, LDL-C); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pregnancy outcomes (preterm birth, fetal growth restriction, low birth weight, etc.); | — |
Countries
China
Contacts
Public ContactLu Cong
Shanghai General Hospital
Outcome results
None listed