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Sugammadex for Laryngeal Polyp Removal Under Laryngoscopy: A Single-Center Randomized Controlled SIingle-Blind Clinical Trial

Sugammadex for Laryngeal Polyp Removal Under Laryngoscopy: A Single-Center Randomized Controlled SIingle-Blind Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114323
Enrollment
Unknown
Registered
2025-12-10
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vocal cord polyps

Interventions

experimental group:administering sugammadex sodium injection for neuromuscular block reversal
control group:dministering neostigmine injection for neuromuscular block reversal

Sponsors

Guabgzhou First People‘s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Volunteers voluntarily cooperate with the study and sign the informed consent form; 2.Age 18-65 years; 3.ASA Class I-III; 4.Planned to undergo vocal cord polyp resection under suspension laryngoscopy;

Exclusion criteria

Exclusion criteria: 1.Known or suspected neuromuscular diseases; 2.Pregnant or lactating women; 3.Participants with known or suspected allergies to sugammadex sodium injection, neostigmine methylsulfate injection, or rocuronium, or those with contraindications to these drugs; 4.Use of other investigational drugs or other interventions for treatment within 6 months; 5.Sufficient recovery of neuromuscular blockade to a Train-of-Four Ratio (TOFR) >= 0.9 upon admission to the Post-Anesthesia Care Unit (PACU); 6.Known or suspected neuromuscular diseases;

Design outcomes

Primary

MeasureTime frame
extubation time;

Secondary

MeasureTime frame
quality of postoperative recovery;Patient Satisfaction;Perioperative Hemodynamics;PACU Length of Stay;

Countries

China

Contacts

Public ContactZheng Bin

Guabgzhou First People‘s Hospital

doczb1006@126.com+86 20 8104 8311

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026