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Effect of ozone autohemotherapy on postoperative delirium and cognitive function in elderly patients undergoing major orthopedic surgery

Effect of ozone autohemotherapy on postoperative delirium and cognitive function in elderly patients undergoing major orthopedic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114320
Enrollment
Unknown
Registered
2025-12-10
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Control gorup:Blank control
Experimental group:Ozone Autohemotherapy

Sponsors

People's Hospital of Jianyang City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Meet the corresponding indications for orthopedic surgery; 2.Expected duration of surgery under general anesthesia > 1 hour; 3.Age >= 60 years; 4.American Society of Anesthesiologists (ASA) physical status I–III.

Exclusion criteria

Exclusion criteria: 1.History of psychiatric disorders; 2.Allergy to ozone or sodium citrate; 3.History of substance abuse or long-term use of medications affecting cognitive function; 4.Inability to communicate effectively; 5.Refusal to participate in the study; 6.Deemed unsuitable for participation by the principal investigator.

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative delirium;

Secondary

MeasureTime frame
Haemodynamics;Complications;Hematological Parameters;Type of Delirium;Sleep quality;Pain score;Duration of delirium;Cognitive dysfunction;Severity of delirium;

Countries

China

Contacts

Public ContactQing Zhong

People's Hospital of Jianyang City

2789545860@qq.com+86 28 27237735

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026