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Clinical observations on microneedle injection of glucocorticoids for l treatment of blepharocysts

A Single-Arm Clinical Trial of Microneedle Injection of Glucocorticoids for the Treatment of Chalazion

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114290
Enrollment
Unknown
Registered
2025-12-10
Start date
2025-12-10
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meibomian gland cysts

Interventions

Trial Group:Instill proparacaine hydrochloride eye drops into the affected eye. Perform routine periorbital disinfection, then inject 0.05–0.15 mL of dexamethasone sodium phosphate injection into the

Sponsors

Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who have been diagnosed with blepharocysts by a doctor; 2. Patients with blepharocysts that have failed conservative treatment ; 3. Volunteer to participate in this study and sign a written informed consent.

Exclusion criteria

Exclusion criteria: 1. patients with a history of allergy to any component of the drugs or tests scheduled for use in the study (e.g., tretinoin, dexamethasone, promethazine hydrochloride, fluorescein); 2. patients with coexisting ocular infections; 3. patients with suspected blepharoplasty tumors; 4. patients with a history of elevated intraocular pressure due to hormonal sensitization; 5. patients who, in the judgment of the investigator, are not suitable for entry into this study.

Design outcomes

Primary

MeasureTime frame
Cyst size;

Secondary

MeasureTime frame
Slit-lamp biomicroscopy examination (including eyelid margin, conjunctiva, cornea, lens, and anterior chamber);

Countries

China

Contacts

Public ContactLi Yingli

Zhujiang Hospital of Southern Medical University

liyingli333@qq.com+86 181 2478 3057

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026