Anxiety and Its Comorbidities
Conditions
Interventions
Group with comorbid anxiety disorder and schizophrenia:None. Conventional treatment for schizophrenia and anxiety disorders
Group with comorbidity of anxiety disorder and depressive disorder:None. Conventional treatment for depression and anxiety disorders
Group with comorbidity of anxiety disorder and bipolar disorder:None. Conventional treatment for bipolar disorder and anxiety disorder
Sponsors
Hangzhou Seventh People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients with anxiety disorders and comorbid conditions (all 4 criteria must be met): (1) Outpatients or inpatients aged between 12 and 75 years old, regardless of gender; (2) Meeting the criteria for anxiety disorders, other mental disorders comorbid with anxiety disorders (such as obsessive-compulsive disorder, depressive disorder, somatoform disorder, mood disorder, bipolar disorder, and sleep disorder), or physical disorders comorbid with anxiety disorders as per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), either for the first onset or recurrence; (3) With a minimum of a primary or secondary education level and able to understand the content of the scale; (4) Understanding and voluntarily participating in this study, and signing the informed consent form by themselves. Inclusion criteria for healthy controls: Age between 12 and 75 years old, in good health without major physical disorders, matching the demographic characteristics of the patients with anxiety disorders and comorbid conditions, and having no history of mental disorders in the past or in the family.
Exclusion criteria
Exclusion criteria: Exclusion criteria for patients with anxiety disorders (exclusion is possible upon meeting any one of the conditions): (1) Deaf-mute individuals, where the dialect is too difficult to understand and communication for assessment is impossible; (2) Organic neurological diseases (such as epilepsy, brain trauma, stroke, encephalitis, etc., brain organic disorders); (3) Unable to complete the survey due to physical conditions (such as: consciousness disorders, coma), and coexisting with severe physical diseases; (4) Pregnant or lactating women; (5) Having implanted medical devices in the body and having contraindications for MRI scanning; (6) Unable to sign the informed consent form for various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Columbia Suicide Severity Scale score;Hamilton Depression Scale score;Hamilton Anxiety Scale score;EEG;Impulsivity Scale 11th Edition;Impulsive-Premeditated Aggressive Behavior Scale score;MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| General demographic information; | — |
Countries
China
Contacts
Public ContactYuqi Cheng
Hangzhou Seventh People's Hospital
Outcome results
None listed