Congenital cataract
Conditions
Interventions
Advanced intraocular lens implantation group:None
Early intraocular lens implantation group:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with significant congenital cataract in one or both eyes. 2. Select primary intraocular lens implantation as the correction strategy for ankylotic eyes. 3. The age at the time of intraocular lens implantation was in line with the exposure group defined in the study (=12 months or > 12 months). 4. The parents or legal guardians of the children patients are willing and able to provide informed consent (for prospective cohorts and children currently under follow-up), or consent to retrospective data retrieval and analysis (for retrospective cohorts), and commit to adhering to the long-term follow-up plan required for the study. 5. (For retrospective data) There are complete postoperative follow-up records, including key information such as visual acuity, diopter, axial length of the eye, and complications.
Exclusion criteria
Exclusion criteria: 1.Congenital cataracts are accompanied by severe systemic diseases that are known to independently and significantly impair the development of visual pathways or overall neurological function (for example, severe neurological deficits, stage 4-5 severe retinopathy of prematurity (ROP), and specific syndromes where visual prognosis is mainly determined by systemic diseases). 2. There are significant ocular comorbidities that are independent and seriously affect visual prognosis, such as microphthalmia (axial length <16 mm), very small corneal size (horizontal diameter <10 mm), optic nerve hypoplasia, or moderate to severe persistent fetal vascular disease (PFV). 3. The affected eye has a history of eye surgery other than congenital cataract extraction. 4. Families are unable or unwilling to adhere to the long-term follow-up plan or participate in necessary vision assessments due to geographical distance, logistical constraints or other factors (prospective cohorts and currently followed children). 5. (For retrospective data) Key data is seriously missing, making it impossible to conduct effective analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stereoscopic vision; | — |
Countries
China
Contacts
Public Contactsiyan Li
Eye Hospital, Wenzhou Medical University
Outcome results
None listed