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The effects of individualized FiO2 combined with individualized PEEP on postoperative atelectasis in patients undergoing robotic surgery: a prospective, randomized controlled trial

The effects of individualized FiO2 combined with individualized PEEP on postoperative atelectasis in patients undergoing robotic surgery: a prospective, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114233
Enrollment
Unknown
Registered
2025-12-09
Start date
2025-12-10
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atelectasis

Interventions

Group F:Individualized inhaled oxygen concentration
Group FP:Individualized inhaled oxygen concentration combined with individualized positive end-expiratory pressure

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age > 18 years old; 2.ASA I-III grade; 3.18 kg/m ² < BMI < 30 kg/m ²; 4. Perform robotic laparoscopic prostate or rectal surgery as scheduled; 5. Be aware of and agree to participate in the trial and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: 1. Severe lung diseases, such as chronic obstructive pulmonary disease, severe asthma, thoracic and spinal deformities, pleural effusion, pneumothorax and huge pulmonary bullae, postoperative pulmonary surgery and other diseases that affect respiratory system compliance; 2. Severe diseases of the heart, liver, kidneys and hematopoietic system; 3. Central neurological diseases with impaired respiratory function; 4. Contraindications for PEEP use: intracranial hypertension, bronchopleural fistula, hypovolemic shock, etc. 5. Hb <110 g/L for females and Hb < 120 g/L for males; 6. Preoperative SpO2 <= 94%; 7. Participated in other clinical studies in the past three months; 8. Patients who refuse to participate in the experiment and cannot cooperate

Design outcomes

Primary

MeasureTime frame
Pulmonary atelectasis;

Secondary

MeasureTime frame
Ventilation parameters;Oxygenation index;

Countries

China

Contacts

Public ContactLijian Chen

The First Affiliated Hospital of Anhui Medical University

chenlijian77@126.com+86 139 6669 9467

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026