Chronic pain
Conditions
Interventions
Chronic pain group:NA
Non-chronic pain group:NA
Sponsors
Qilu Hospital, Shandong University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: Case Group (Chronic Pain Group) Inclusion Criteria: 1. Age >= 20 years old, willing and able to sign a written informed consent form; 2. Inpatients referred from the Pain Clinic or admitted/hospitalized for chronic pain. Meets chronic pain definition: Pain persisting or recurring for >= 3 months (per IASP/study definition), with at least one episode lasting >= 24 hours within the past month; 3. Able to complete interviews cooperatively; 4. Has routine admission laboratory tests and accessible fasting blood test results collected within the past 7 days (or within 72 hours prior to enrollment): CRP, fasting plasma glucose (FPG), and triglycerides (TG). FPG/TG blood draws require >=8 hours of fasting. Control Group (No Chronic Pain Group) Inclusion Criteria: 1. Age >= 20 years old, willing and able to sign a written informed consent form; 2. Hospitalized patients with no history of chronic pain (no history of persistent or intermittent pain lasting >= 3 months, and no episodes of persistent pain lasting >= 24 hours within the past month); Inclusion confirmed via brief interview dialogue verifying "no history of chronic pain or recent chronic pain episodes"; 3. Availability of fasting CRP, FPG, and TG test results collected within the past 7 days (or within 72 hours prior to enrollment); 4. Ability to cooperate with the interview process.
Exclusion criteria
Exclusion criteria: Case Group (Chronic Pain Group) Exclusion Criteria: 1. Postoperative acute pain (within = 38.0°C) to avoid significant CRP interference from acute inflammation; 3. Use of systemic glucocorticoids or immunosuppressants within 1 month prior to enrollment, or recent high-dose antibiotic/anti-inflammatory therapy (potentially affecting CRP/TG/FPG); 4. Active malignancy, severe organ failure (cardiac, hepatic, renal insufficiency), or end-stage disease; 5. Severe cognitive impairment, inability to complete interview dialogue, or incapacity to sign informed consent; 6. Pregnant or lactating women. Control Group (Non-Chronic Pain Group) Exclusion Criteria: 1. Recent (within 2 weeks prior to enrollment) acute infection/fever; 2. Use of systemic glucocorticoids or immunosuppressants within 1 month prior to enrollment; 3. Active malignancy, severe organic disease, or end-stage disease; 4. Severe cognitive impairment or inability to complete interview dialogue and sign informed consent; 5. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chronic pain;C-Reactive Protein-Triglycerides-Glucose Index (CTI); | — |
Countries
China
Contacts
Public ContactFeng Qi
Qilu Hospital, Shandong University
Outcome results
None listed