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Ketoprofen gel plaster after total knee arthroplasty in patients with severe knee osteoarthritis: a randomized controlled trial

Ketoprofen gel plaster after total knee arthroplasty in patients with severe knee osteoarthritis: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114221
Enrollment
Unknown
Registered
2025-12-09
Start date
2026-01-31
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Control group:Patients with knee osteoarthritis were given routine treatment and nursing after operation
Research Group:Ketoprofen gel plaster was added to the conventional treatment

Sponsors

Qilu Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. All subjects voluntarily agreed to participate in this study and signed a written informed consent. 2. Age 40-75 years old, male or female; 3. patients who met the indications of total knee arthroplasty, underwent the first unilateral operation;

Exclusion criteria

Exclusion criteria: 1. congenital malformation or ankylosing spondylitis; 2. complicated with severe cardiovascular and cerebrovascular diseases; 3. complicated with severe mental disorders; 4. pregnant and lactating women or women of childbearing age who are trying to become pregnant; 5. other conditions considered by the investigator to be inappropriate for participation in the trial.

Design outcomes

Primary

MeasureTime frame
VAS score;KSS score;

Secondary

MeasureTime frame
Evaluation of safety;

Countries

China

Contacts

Public ContactLiu Shenghou

Qilu Second Hospital of Shandong University

2228180977@qq.com+86 176 6008 1521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026