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Intelligent prediction of post-extraction orthodontic soft-tissue facial profile based on multimodal three-dimensional data(soft-tissue response characteristics)

Intelligent prediction of post-extraction orthodontic soft-tissue facial profile based on multimodal three-dimensional data(soft-tissue response characteristics)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114214
Enrollment
Unknown
Registered
2025-12-09
Start date
2025-12-22
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malocclusion

Interventions

Sponsors

Peking University Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1.Han Chinese patients aged 14–35 years at the start of orthodontic treatment; 2.No severe skeletal discrepancy (-1.3° < ANB < 6.7°); 3.Systemically healthy; 4.Body mass index (BMI) within the normal range of 18–24 kg/m²; 5.Availability of pre-treatment large-field CBCT and 3D facial scans with complete and analyzable image data;

Exclusion criteria

Exclusion criteria: 1.Previous orthodontic treatment (excluding early interceptive treatment); 2.Severe facial asymmetry (horizontal deviation of the chin > 3 mm); 3.Congenital craniofacial anomalies or syndromes; 4.History of facial soft-tissue defects or trauma; 5.Dental defects or missing teeth (except for cases in which premolar spaces are closed and regarded as extraction cases);

Design outcomes

Primary

MeasureTime frame
Three-dimensional coordinates of facial soft-tissue landmarks;Change in soft tissue volume;Facial protrusion and curvature variation indicators;

Secondary

MeasureTime frame
Symmetry change score;

Countries

China

Contacts

Public ContactWenhsuan Lu

Peking University Hospital of Stomatology

wenhsuanlu@163.com+86 10 8219 5330

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026