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The effect of intraoperative calcium supplementation on sleep disorders after surgical anesthesia: a randomized controlled, double-blind trial

The effect of intraoperative calcium supplementation on sleep disorders after surgical anesthesia: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114209
Enrollment
Unknown
Registered
2025-12-09
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sleep disorders

Interventions

Calcium chloride group:Administer 1g of calcium chloride during surgery, dilute with physiological saline to 50ml, and continue infusion for 1 hour.
Control group:Administer 50ml of physiological saline and continuously infuse for 1 hour during the operation. 20/1000 ,50ml1 Administer 50ml of physiological saline and continuously infuse for 1 h

Sponsors

Qilu Hospital (Qingdao),Cheeloo College of Medicine,Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients who voluntarily sign informed consent forms and plan to undergo elective laparoscopic surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: Patients with expected surgical duration less than 1 hour, age less than 18 years old or over 80 years old, hypercalcemia, severe liver and kidney diseases, cardiovascular and cerebrovascular diseases, weight less than 50kg or greater than 100kg, treated with oral calcium ion blockers 48 hours before surgery, patients receiving digoxin treatment 48 hours before surgery, patients with preoperative renal dysfunction (blood creatinine greater than 1mg/dl), patients with a history of arrhythmia or congenital heart disease or a mother with a clear history of arrhythmia or congenital heart disease, patients with blood pressure exceeding 160mmHg or diastolic blood pressure exceeding 110mmHg requiring intravenous hypotension treatment, patients receiving intraoperative blood transfusion treatment, and patients deemed unsuitable by researchers to participate.

Design outcomes

Primary

MeasureTime frame
Incidence of sleep disorders 1 days after surgery;

Secondary

MeasureTime frame
Number of awakenings at night;Sleep Incidence of daytime sleepines;Postoperative VAS pain score;Sleep quality;Nausea and vomiting;Arrhythmia;Hypertension;Blood loss;

Countries

China

Contacts

Public ContactWenyuan Lv

Qilu Hospital (Qingdao),Cheeloo College of Medicine,Shandong University

lwyjerry@163.com+86 185 6181 1387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026