Surgery for Severe Pancreatitis
Conditions
Interventions
SURGICEL hemostatic granules group:None
ARISTA hemostasis powder group:None
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnosis of acute pancreatitis/pancreatitis necrosis and need surgical treatment; 2. Aged 18-74 years; 3. Patients with SBSS bleeding score of grade 3 or below; 4. Provide signed and dated informed consent.
Exclusion criteria
Exclusion criteria: 1. Coagulation insufficiency: Patients with blood system diseases (such as hemophilia), severe liver and kidney dysfunction (Child classification C for liver function), prothrombin time (PT)>18 seconds or activated partial thromboplastin time (APTT)>52 seconds; 2. Pregnant or lactating women; 3. Patients who have recently participated in other clinical trials; 4. Subjects who took heparin 12 hours before the operation or took coumarin (warfarin) and/or X-a factor inhibitors orally within 3 days before the operation; Subjects who received antiplatelet /P2Y12 inhibitor drug treatment within 5 days before the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success rate of hemostasis on the flat wound was 3 minutes; | — |
Secondary
| Measure | Time frame |
|---|---|
| The success rate of hemostasis on the flat wound was 5 minutes;The success rate of hemostasis on flat wound in 10 minutes;Hemostatic time [Hemostatic time for the product];The amount of wound bleeding;Total operative time;The proportion of intraoperative lens blur;Postoperative Blood Transfusion Volume(Within 3 days after surgery);Postoperative Blood transfusion Volume (within 3 days);Change in Hemoglobin (Hb);Postoperative Drainage Volume (Within 3 Days After Surgery);Postoperative Drainage Duration;Rate of Reoperation(Within 3 Days After Surgery);Rate of Moderate to Severe Bleeding-Related Adverse Reactions(Up to Discharge);Cost of Hemostatic Materials;Usage Quantity of Hemostatic Materials (Vial(s));Hospitalization Costs;Postoperative Hospitalization Time;Hospitalization Time; | — |
Countries
China
Contacts
Public ContactLu Huimin
West China Hospital of Sichuan University
Outcome results
None listed