Chronic Consciousness Disorders
Conditions
Interventions
Group A: Conventional rehabilitation therapy andTrigeminal nerve electrical stimulation combined with electric standing bed therapy
GroupB:Conventional rehabilitation therapy and trigeminal nerve electrical stimulation therapy
GroupC:Conventional rehabilitation therapy and electric standing bed therapy
Sponsors
The Second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: To be eligible for inclusion, all of the following criteria must be met: 1. Age >=18 years; 2. Duration of unconsciousness > 28 days; 3. Diagnosed with persistent vegetative state (PVS) or minimally conscious state (MCS) according to clinical diagnostic criteria and the Coma Rating Scale-Revised (CRS-R); 4. Causes include hypoxia, trauma, and stroke; 5. No prior history of neurological disease.
Exclusion criteria
Exclusion criteria: Exclusion criteria: meet any one of the following: 1. Unstable vital signs; 2. Severe pulmonary infection; 3. Uncontrollable severe infection; 4. Concurrent dysfunction of vital organs (heart, liver, kidneys, etc.) or coagulation disorders; 5. Organ transplant recipients or patients with severe autoimmune diseases; 6. Patients with cachexia due to advanced malignancy or critically low peripheral blood counts; 7. Patients with elevated intracranial pressure; 8. Individuals deemed by the physician to be at high risk of non-compliance with follow-up appointments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coma Recovery Scale-Revised;Glasgow Coma Scale;Bedside functional near-infrared spectroscopy imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| electroencephalogram;event-related potential; | — |
Countries
China
Contacts
Public Contactxuchunyan
The Second Affiliated Hospital of Kunming Medical University
Outcome results
None listed