Metabolic syndrome
Conditions
Interventions
control :Lifestyle intervention
experimental :Lifestyle + probiotics + prebiotic intervention
Sponsors
Shulan (Hangzhou) Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 18 - 65 years old, gender not restricted 2. Sign the informed consent form 3. Those meeting the diagnostic criteria for metabolic syndrome (refer to the International Diabetes Federation IDF 2005)
Exclusion criteria
Exclusion criteria: 1. Those with severe disorders of the heart, liver and kidneys, or malignant tumors. 2. Those who have taken drugs that can alter the intestinal microecology and body metabolism within the last 4 weeks, such as antibiotics, antiviral drugs, probiotic-related preparations, cytotoxic drugs, hormones, etc. 3. Those who have participated in other clinical studies within the last 4 weeks or are currently participating in such studies. 4. Those with digestive system diseases such as inflammatory bowel disease, irritable bowel syndrome, chronic diarrhea, etc. 5. Pregnant or lactating women. 6. Those with an unstable dietary history, defined as significant changes in diet within the last month, including a reduction or significant increase in the main food groups in the diet of the subjects. 7. Those with a long-term and heavy drinking history. 8. The researchers consider that they have other conditions that make them unsuitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change rate of HOMA-IR;Improvement rate of metabolic indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Gut Microbiota Abundance and Diversity; | — |
Countries
China
Contacts
Public ContactXiahong Dai
Shulan (Hangzhou) Hospital
Outcome results
None listed