Preeclampsia
Conditions
Interventions
Control group:None
Sponsors
Hangzhou First People's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.Preeclampsia Group: Pregnant women; aged 18–45 years; meeting the International Federation of Gynecology and Obstetrics (FIGO) diagnostic criteria for preeclampsia; singleton pregnancy; voluntarily signed informed consent; 2.Normal control group: Pregnant women; aged 18–45 years; healthy pregnant women; no gestational hypertension, proteinuria, or other severe pregnancy complications; singleton pregnancy; full-term delivery; voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Preeclampsia Group: Comorbidities with other severe pregnancy complications (e.g., HELLP syndrome, placental abruption); Comorbidities with chronic hypertension, diabetes, autoimmune diseases, or severe infections; Multiple pregnancies or fetal congenital anomalies; Recent use of immunosuppressive agents or anti-inflammatory drugs; 2.Normal control group: History of gestational hypertension, preeclampsia, or other pregnancy complications; concomitant chronic diseases (e.g., hypertension, diabetes, autoimmune disorders); multiple pregnancies or fetal abnormalities; recent use of medications that may affect immune function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Macrophage Polarization Analysis;NF-?B Pathway Activation Detection;LYN Expression; | — |
Countries
China
Contacts
Public ContactLian Yunyun
Hangzhou First People's Hospital
Outcome results
None listed