Sarcopenia
Conditions
Interventions
Intervention group:The intervention group was given CaHMB high-protein nutritional special powder, 15g daily, for 12 consecutive weeks.
Control group:The control group was given a high-protein nutritional special powder without CaHMB, 15g daily for 12 consecutive weeks.
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.age-related sarcopenia (fractures, degenerative osteoarthritis, osteoporosis, etc.); 2.age >=60 years, any gender or ethnicity; 3.meeting the Asian Working Group for Sarcopenia (AWGS) diagnostic criteria for sarcopenia, fulfilling the following conditions: (1)Reduced skeletal muscle mass, defined as BIA measurement with ASMI <7.0 kg/m² for men and <5.7 kg/m² for women, or DXA measurement with ASMI <7.0 kg/m² for men and <5.4 kg/m² for women; (2)Simultaneously meeting the criteria for decreased skeletal muscle strength, defined as handgrip strength <26 kg for men and <18 kg for women, or reduced physical performance, defined as gait speed <0.8 m/s; 4.able to tolerate enteral nutrition; 5.voluntarily agrees to and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Individuals who cannot tolerate enteral nutrition; 2.those with diseases that severely affect the digestion and absorption of the test product (such as short bowel syndrome or severe enteritis); 3.patients with severe cardiac, hepatic, or renal dysfunction, serious neuropsychiatric disorders, or tumors who are undergoing radiotherapy or chemotherapy, as well as patients with edema; 4.those currently using other nutritional preparations that may affect the study outcomes; 5.patients using medications that may influence the study results (such as hormones, antitumor drugs, sedatives, or other muscle relaxants); 6.individuals whom the investigator deems unsuitable for participation in this study; 7.and those who have not signed the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Indices of skeletal muscles in limbs, ASMI;Advantageous grip strength;6-Meter Walking Speed Test;Complete Blood Count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum albumin;Body Mass Index, BMI;Upper arm circumference;Calf circumference; | — |
Countries
China
Contacts
Public ContactYu Sun
Northern Jiangsu People's Hospital2025
Outcome results
None listed