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Research on Biomarkers, Influencing Factors, and Longitudinal Trajectories of Anxiety and Depression in Patients with Spontaneous Intracerebral Hemorrhage

A Study on Blood Biomarkers, Influencing Factors, and Longitudinal Trajectories of Anxiety and Depression in Patients with Spontaneous Intracerebral Hemorrhage

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114125
Enrollment
Unknown
Registered
2025-12-08
Start date
2025-12-10
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneous intracerebral hemorrhage, post-stroke depression, post-stroke anxiety, etc

Interventions

Sponsors

The Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed as spontaneous intracerebral hemorrhage confirmed by cranial CT; 2. Onset to admission =18 years old; 4. Received neurosurgical treatment; 5. The patient themselves or their legal representative must understand the research purpose and procedures and sign a written informed consent form; 6. The patient or their family can provide valid contact information, with at least 2 contacts upon enrollment (immediate family members + the patient), recording WeChat/phone/address; verify and update each contact.

Exclusion criteria

Exclusion criteria: 1. Non-spontaneous intracerebral hemorrhage: such as traumatic intracerebral hemorrhage, hemorrhagic transformation following brain tumor, cerebral aneurysm, arteriovenous malformation, vasculitis, or cerebral infarction; 2. Special etiology: bleeding caused by excessive anticoagulant/fibrinolytic drug use, severe coagulation dysfunction (such as hemophilia), etc; 3. History of pre-existing mental illness: Individuals with a confirmed diagnosis of schizophrenia, bipolar disorder, or severe depression before admission and who have been on long-term medication treatment; 4. Severe comorbidities: end-stage tumors, severe heart, liver, or kidney dysfunction, or an estimated survival period =3 at admission, unable to live independently; 7. Pregnant or lactating women; 8. Refusal to participate or inability to obtain a written informed consent signed by the patient /legal representative.

Design outcomes

Primary

MeasureTime frame
Post-stroke depression (PSD) incidence;

Secondary

MeasureTime frame
Post-stroke anxiety (PSA) incidence;mRS score;

Countries

China

Contacts

Public ContactZhou Jie

The Affiliated Hospital of Southwest Medical University

zj000718@yeah.net+86 15808498258

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026