Aortic coarctation
Conditions
Interventions
Dual Aortic Cannulation Group:None
Deep Hypothermic Circulatory Arrest Group:None
Selective Antegrade Cerebral Perfusion Group:None
Sponsors
West China Second University Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: (1) Age of 0 to 11+ months; (2) Aortic arch reconstruction under cardiopulmonary bypass;
Exclusion criteria
Exclusion criteria: (1) The intraoperative perfusion strategy records were missing, and the perfusion strategy could not be judged. (2) Preoperative neurological complications; (3) Previous cardiac surgery history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of major adverse events during hospitalization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative incidence of low cardiac output syndrome (LCOS);Peak lactate levels (mmol/L) at 24, 48, and 72 hours postoperatively;Maximum VIS (vasoactive-inotropic score) within 24, 48, and 72 hours postoperatively;Duration of postoperative inotropic support (days);Echocardiography on the first day after surgery LVEF (%) and LVEDVI (mL/m2);Lowest intraoperative NIRS values ??(%) in the brain and lumbar region within 24 hours postoperatively;Incidence of postoperative hepatic dysfunction;Respiratory function: PaO?/FiO? ratio 24, 48, and 72 hours after surgery;3)Postoperative incidence of major gastrointestinal complications;4)Postoperative incidence of multiple organ dysfunction syndrome (MODS)/failure;Intraoperative blood transfusion volume (mL/kg);2)Chest tube drainage output during the first 24 hours after surgery (mL/kg);Cardiac-related rehospitalization rates at 30 days, 1 year, and during long-term follow-up;2)Cardiac-related reoperation rates at 30 days, 1 year, and during long-term follow-up;Survival status due to cardiac reasons at 30 days, 1 year, and during long-term follow-up;Total operative time (min);Cardiopulmonary bypass (CPB) duration (min);Aortic cross-clamping time (min);Circulatory arrest duration (min)/ SACP time (min);Cerebral NIRS minimal intraoperative (%) ;Lumbar NIRS minimal intraoperative (%) ;Peak lactate level during CPB (mmol/L);Postoperative surgical complications including diaphragmatic paralysis, recurrent laryngeal nerve injury, chylothorax, deep wound infection, mediastinitis, pulmonary artery stenosis and bronchomalacia;Postoperative residual lesion score (RLS);Duration of mechanical ventilation (min);Intensive care unit (ICU) length of stay (days);Total length of stay in the hospital (days);Delayed sternal closure rate and closure delay time (days); Re-sternotomy rate and time to reoperation (days);Extracorporeal membrane oxygenation (ECMO) utilization rate and support duration (days);Unplanned reoperation rate during hospitali | — |
Countries
China
Contacts
Public ContactShuhua Luo
West China Second University Hospital, Sichuan University
Outcome results
None listed