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Randomized and controlled clinical trials to evaluate the therapeutic effect of bioassembled polymer desensitizers on dentin sensitivity

Randomized and controlled clinical trials to evaluate the therapeutic effect of bioassembled polymer desensitizers on dentin sensitivity

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114116
Enrollment
Unknown
Registered
2025-12-08
Start date
2025-12-08
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin sensitivity

Interventions

Control group:Receive treatment with Gluma desensitizer
Trial group:Receive treatment with bioassembled polymer desensitizers

Sponsors

Beijing Stomatological Hospital , Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1. Age >=18 years old and =4, and the wear index TWI is 2 or 3;

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to product ingredients and react to characteristics; 2. Those who have a history of medical treatment that may affect desensitization treatment (such as periodontal scraping, periodontal surgery or orthodontic treatment, other desensitization treatment) and drug treatment that may affect desensitization treatment, including long-term use of anti-inflammatory, analgesic and mind-altering drugs; 3. There is a plan to change the daily oral care habits in the next 6 months; 4. People with eating disorders in the past month (abnormal eating behavior >=1 attacks a week, including three categories of anorexia nervosa, bulimia nervosa and bulimia); 5. Systemic diseases that cause or are prone to dentin allergy (such as chronic acid reflux); 6. Excessive exposure to acid in the diet or environment; 7. Have a dental treatment plan in the next 6 months; 8. Pathology or defects with any other pain in the teeth or supporting structure (such as abnormal tooth development, dentin hypoplasia, enamel hypoplasia, tetracycline teeth, fluorine plaque, etc.); 9. The affected teeth have other dental diseases that can cause pain similar to dentin sensitivity, such as hidden fissure, caries, pulpitis, crowns, fixed or movable dentures, or large-area fillings; 10. Those with severe periodontitis, or moderate periodontitis active inflammation or advanced period; 11. Pregnant and lactating women; 12. Those who have participated in other clinical trials in the past three months; 13. People with mental disabilities or intellectual disabilities.

Design outcomes

Primary

MeasureTime frame
The rate of sensitivity relief at 6 months post-treatment (percentage reduction in VAS score);

Countries

China

Contacts

Public ContactLiu Min

Beijing Stomatological Hospital , Capital Medical University

sdyd2314@163.com+86 10 57099280

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026