Postoperative care following gynaecological laparoscopy
Conditions
Interventions
Experimental group:Anaesthetic induction was achieved using remimazolam tosylate 0.3–0.4 mg/kg, sufentanil 0.4–0.6 µg/kg, and rocuronium bromide 0.6–0.9 mg/kg. Intraoperatively, remimazolam tosylate 1
Control group:Anaesthetic induction was achieved using remimazolam tosylate 0.3–0.4 mg/kg, sufentanil 0.4–0.6 µg/kg, and rocuronium bromide 0.6–0.9 mg/kg. Intraoperatively, remimazolam tosylate 1–3 mg
Sponsors
Henan Univ,Huaihe Hosp
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Female patients aged 18–65 years; 2. ASA physical status classification I–III (American Society of Anesthesiologists); 3. Elective gynaecological laparoscopic surgery (including myomectomy, ovarian cystectomy, hysterectomy, etc.); 4. Apfel simplified risk score >= 3 points (indicating high risk for PONV); 5. Voluntary participation in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe combined dysfunction of vital organs including heart, liver, and kidneys; 2. Long-term opioid use or chronic pain syndrome; 3. Known allergy to any medication used in the study; 4. History of substance abuse or alcohol dependence; 5. Pregnant or breastfeeding women; 6. Other circumstances deemed unsuitable for study participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete resolution rate of PONV within 24 hours post-surgery;PONV Severity Score;VAS;Use of anti-emetic and analgesic drugs during labour;Time of first ambulation;Initial venting time;First bowel movement;Length of stay, hospital charges; | — |
Countries
China
Contacts
Public ContactXin Wenqi
Huaihe Hospital of Henan University
Outcome results
None listed