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Evaluation of the effect of intraanal iodine disinfection in preventing perianal infection in acute leukemia patients

Evaluation of the effect of intraanal iodine disinfection in preventing perianal infection in acute leukemia patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114102
Enrollment
Unknown
Registered
2025-12-08
Start date
2025-12-14
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Leukemia

Interventions

Traditional Nursing Group:Sitz bath with 1500ml of 0.5% iodophor solution, keep the sitz bath liquid temperature at 38?~41?, and the sitz bath time is 10~15 minutes.
Intervention group:3 pieces of disposable cotton swabs were used to absorb 3ml of 5% iodine solution. The first swab was used to disinfect the skin folds of anus in a ring, the second swab was used to
Strong intervention group:Take 4 disposable cotton swabs and absorb 4ml of 5% iodine tincture. The first swab is used to disinfect the anal skin folds in a circular motion. The second swab is inserted

Sponsors

The First Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Meets the diagnostic criteria for acute leukemia in the 'Diagnosis and Therapeutic Efficacy Standards of Hematological Diseases (4th Edition)'; (1) Age >= 18 years old; (2) Peripheral blood monitoring shows absolute neutrophil count < 1.0×10^9/L; (3) The patient and their family have been informed about the content of this study and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with perianal infection present before admission or before the absolute neutrophil count in peripheral blood is <1.0*10^9/L; (2) Patients who have undergone surgery for perianal abscess or anal fistula; (3) Patients with concomitant mental illness.

Design outcomes

Primary

MeasureTime frame
Perianal infection incidence;

Secondary

MeasureTime frame
Patient's perianal pain score;Patient compliance rate;

Countries

China

Contacts

Public ContactWang Zhudan

The First Affiliated Hospital of Zhejiang University School of Medicine

Wangzd1106@163.com+86 135 8813 4196

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026