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Study on the synergistic rehabilitation mechanism of upper limb function and executive function of hemiplegic patients with acquired brain injury by fNIRS based motion simulation game

Study on the synergistic rehabilitation mechanism of upper limb function and executive function of hemiplegic patients with acquired brain injury by fNIRS based motion simulation game

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114098
Enrollment
Unknown
Registered
2025-12-08
Start date
2025-12-22
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired brain injury

Interventions

Experimental group:Accept a 4-week routine rehabilitation training and sports simulation game training
Control group:Accept a 4-week routine rehabilitation training

Sponsors

China Rehabilitation Research Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Head CT or MRI diagnosis confirms stroke or traumatic brain injury, and imaging examination shows no moderate or severe brain atrophy or white matter rarefaction; (2) First onset, normal executive function before onset (3) Upper limb Fugl Meyer score (FMA-UE) of 20-45 (moderate functional impairment) (4) Montreal cognitive assessment (MoCA) indicating executive dysfunction (5) Basic visual tracking ability (>= 0.6 after visual correction) (6) Voluntary participation and completion of experimental tasks, signing of informed consent form.

Exclusion criteria

Exclusion criteria: (1) Upper limb spasms (modified Ashworth >= 2) or pain (VAS >= 4) (2) History of epilepsy or risk of photosensitive epilepsy (3) Severe cardiopulmonary dysfunction (NYHA III-IV) (4) Other clinical trial interventions received in the past month (5) Obvious aphasia, agnosia, hearing impairment, and visual impairment during testing, visual field defects and unilateral neglect (star scratch test<51 points), red green color blindness (6) Accompanied by neurological disorders other than brain damage, psychiatric disorders, and other serious internal and external diseases, uncooperative examination, taking psychiatric medication.

Design outcomes

Primary

MeasureTime frame
Fugl Meyer score for upper limbs;Executive Function Performance Test;Functional Near Infrared Spectroscopy;

Secondary

MeasureTime frame
Montreal Cognitive Assessment;LotCA, Loewenstein Occupational Therapy Cognitive Assessment;

Countries

China

Contacts

Public ContactYaning Cheng; Lixu Liu

China Rehabilitation Research Center

Chengyn0715@163.com+86 177 1059 1380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026