prostatic cancer
Conditions
Interventions
Index test:Detection of PCA3 and PSA gene expression in morning urine (fluorescence PCR)
Sponsors
Beijing Shijitan Hospital, Capital Medical University
Eligibility
Sex/Gender
Male
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged 45 years and above who meet any of the following requirements for a prostate biopsy: 1. DRE found suspicious prostate nodules, any PSA value; 2. suspicious lesions were found by transrectal ultrasound or MRI, with any PSA value; 3. PSA>10ng/ml; 4. PSA4~10ng/ml, the ratio of free PSA to total PSA is suspicious or the PSA density value is suspicious.
Exclusion criteria
Exclusion criteria: 1. Patients who have not completed prostate puncture examination and cannot be diagnosed; 2. Subjects who have been treated with antiandrogen drugs within one year; 3. Subjects with previous history of prostate cancer or prostate cancer surgery; 4. The researcher thinks it is not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity;specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| PCA3 gene;PSA gene; | — |
Countries
China
Contacts
Public ContactLiu Na
Beijing Shijitan Hospital, Capital Medical University
Outcome results
None listed