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The influence of liposomal bupivacaine for distal forearm peripheral nerve block on rebound pain after nerve block and postoperative rehabilitation in patients with hand trauma

The influence of liposomal bupivacaine for distal forearm peripheral nerve block on rebound pain after nerve block and postoperative rehabilitation in patients with hand trauma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114087
Enrollment
Unknown
Registered
2025-12-08
Start date
2025-04-24
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rebound pain after peripheral nerve block

Interventions

Bupivacaine liposome group:The bupivacaine liposome group (Group L) performed peripheral nerve block distally for postoperative pain management: Under ultrasound guidance, the nerves to be blocked wer
Bupivacaine group:performed peripheral nerve block distally for postoperative pain management: Under ultrasound guidance, the nerves to be blocked were selected based on the nerve innervation involved
Control group:After the completion of a routine interscalene brachial plexus block, no further intervention was performed.

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Select patients with hand injuries ; 2.no gender limitation; 3.aged between 18 and 65 years; 4.BMI 18 to 30 kg/m^2; 5.ASA grade I or II; 6.The surgical area involves the areas innervated by the radial nerve, the median nerve and/or the ulnar nerve;

Exclusion criteria

Exclusion criteria: 1. Combined peripheral neuropathy; 2. Infection at the puncture site; 3. Abnormal coagulation function; 4. Combined forearm or upper arm trauma, combined with injuries in other parts of the body; 5. Local anesthetic allergy

Design outcomes

Primary

MeasureTime frame
The incidence of rebound pain after nerve block surgery;

Secondary

MeasureTime frame
Postoperative pain score;Duration of sensory/motor blockage;15-item Quality Recovery Rating Scale;

Countries

China

Contacts

Public ContactZhang Xuekang

The First Affiliated Hospital of Nanchang University

Kang7139@163.com+86 138 7063 9612

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026