Breast disease
Conditions
Interventions
Trial group:Administer 2-3 sprays of dexmedetomidine nasal spray after entering the waiting area.
Control group:Preoperative administration of an equal amount of normal saline as the experimental group
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.18-65-year-old female patient undergoing breast surgery; 2. BMI 15-28; 3. ASA grades I-II; 4. No history of antipsychotic medication.
Exclusion criteria
Exclusion criteria: 1.Have a history of central system diseases such as epilepsy; 2.Long-term users of primary sleep disorder; 3.Patients with chronic sinusitis and other nasal diseases; 4.Severe bradycardia (heart rate < 50 beats/min) or atrioventricular block above grade II.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety score;Postoperative anxiety and sleep status; | — |
Secondary
| Measure | Time frame |
|---|---|
| Non-Invasive Blood Pressure;Heart rate;Blood oxygen saturation;Bispectral index;Extubation time;Post-anesthesia care unit (PACU) length of stay;Postoperative recovery quality;Peripheral Oxygen Saturation;Dosage/Usage of Propofol and Remifentanil during Surgery; | — |
Countries
China
Contacts
Public ContactHan Qi
Weifang People's Hospital
Outcome results
None listed