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Mechanisms and Parameter Optimization of Acupuncture Combined with rTMS for Post-Stroke Upper Limb Dysfunction Based on Brain Imaging under Different Intervention Sequences

Mechanisms and Parameter Optimization of Acupuncture Combined with rTMS for Post-Stroke Upper Limb Dysfunction Based on Brain Imaging under Different Intervention Sequences

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114073
Enrollment
Unknown
Registered
2025-12-08
Start date
2025-07-10
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Acupuncture-first group:(1) rTMS was used in conventional drug treatment and conventional rehabilitation training at the same time. The magnetic stimulation was performed by the magnetic stimulator (m
rTMS-first group:(1) rTMS was used in conventional drug treatment and conventional rehabilitation training at the same time. The magnetic stimulation was performed by the magnetic stimulator (model YR
Simultaneous-treatment group:(1) rTMS was used in conventional drug treatment and conventional rehabilitation training at the same time. The magnetic stimula

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients met the diagnostic criteria of "Chinese Guidelines for the Diagnosis and Treatment of Cerebral Hemorrhage (2019)" or "Chinese Guidelines for the diagnosis and treatment of acute ischemic Stroke (2018)" and were diagnosed by head CT or MRI examination; (2) primary, unilateral, or previous attacks without neurological deficits; (3) Stable vital signs and clear consciousness; (4) Brunnstrom grade of the upper limb was stage I-IV. (5) Aged between 18 and 75 years; (6) The course of disease ranged from 2 weeks to 6 months; (7) Transcranial magnetic stimulation could detect motor evoked potential in the contralateral brain region; (8) Informed consent was obtained from enrolled patients.

Exclusion criteria

Exclusion criteria: (1) upper limb movement disorders caused by other causes before the onset; (2) unstable conditions such as recurrent cerebral infarction or cerebral hemorrhage during hospitalization; (3) severe audio-visual impairment, speech or cognitive impairment, unable to understand and cooperate with treatment and evaluation; (4) history of skull fracture and/or severe head injury, head and/or brain surgery; (5) with transcranial magnetic contraindications: metal foreign body in the head, cardiac pacemaker, wearing ear hearing aid, increased intracranial pressure, epilepsy or family history of epilepsy.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Upper Extremity Motor Function Rating Scale;Functional magnetic resonance imaging;Motor evoked potential;

Secondary

MeasureTime frame
Modified Barthel Index;

Countries

China

Contacts

Public ContactQian Yu

Sichuan Provincial People's Hospital

yqswc11@163.com+86 189 8183 8959

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026