Stroke
Conditions
Interventions
Cognitive-Motor Interactive Training Group:Cognitive-Motor Interactive Training Protocol:
The intervention program is based on a goal-directed cognitive-motor dual-task paradigm, integrating music the
Frequency: 5 sessions/week
Total intervention period: 4 weeks
Computer-Assisted Cognitive Training Group:Computer-Assisted Cognitive Training Protocol:
The intervention program utilizes computerized cognitive rehabilitation training modules, delivered through sp
Conventional Cognitive Rehabilitation Training Group:Conventional Cognitive Rehabilitation Training Group
The conventional cognitive rehabilitation training protocol was implemented in accordance with
Frequency: 5 sessions per week
Stroke group (cross-sectional part):None
Health Group (Cross-Sectional Part):None
Sponsors
Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Stroke Patients: 1.Diagnosis of stroke according to the 2019 Chinese Diagnostic Criteria for Major Cerebrovascular Diseases (including diagnostic standards for cerebral infarction and intracerebral hemorrhage), confirmed by CT or MRI; 2.Age 18–80 years, regardless of gender; 3.First-ever stroke, with disease duration between 2 weeks and 6 months; 4.Cognitive impairment, defined as a MoCA score <26; 5.Voluntary participation with signed informed consent; Patients meeting all the above criteria will be enrolled in the study; Inclusion Criteria for Healthy Participants: 1.Aged between 18 and 80 years, with no restrictions on gender; 2.Ability to understand and provide written informed consent, and voluntary participation in the study.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Stroke Patients: 1.Aphasia (e.g:Boston Diagnostic Aphasia Examination score = Grade 3) or other conditions impeding cognitive training; 2.History of dementia or significant intellectual decline; 3.Severe comorbidities, including:Hearing/visual impairments;Psychiatric disorders;Cardiac diseases;Malignancies;Hepatic/renal failure;Major gastrointestinal bleedin 4.Concurrent participation in other clinical trials that may confound study outcomes. Exclusion Criteria for Healthy Participants: 1.Individuals who meet the diagnostic criteria for major depressive disorder, psychotic disorders, etc., according to the DSM-5; 2.History of any significant medical, neurological, or psychiatric illness; pregnancy; head trauma; or alcohol or substance abuse; 3.Concurrent participation in any other clinical trial that may interfere with the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (Fuzhou Version) (MoCA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Trial Making Test-A/B,TMT-A/B;Chinese auditory learning test, AVLT;Digital Span, DS;Digital vigilance test, DVT;Symbol digital modalities test, SDMT;Upper Limb Kinematic Characteristics Assessment;Manual Muscle Testing,MMT;Modified Barthel Index, MBI; | — |
Countries
China
Contacts
Public ContactYang Shanli
Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Outcome results
None listed