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Efficacy of intense pulsed light with optimal pulse technology for Meibomian Gland Dysfunction-Related Dry Eye and a Lipidomics Study

Efficacy of intense pulsed light with optimal pulse technology for Meibomian Gland Dysfunction-Related Dry Eye and a Lipidomics Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114047
Enrollment
Unknown
Registered
2025-12-05
Start date
2025-12-08
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meibomian Gland Dysfunction-Related Dry Eye

Interventions

Observation group:none
Control group:none

Sponsors

Qilu Hospital of Shandong University Dezhou Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: It simultaneously meets the diagnostic requirements of the 2020 Chinese Expert Consensus on Dry Eye and the 2023 Chinese Expert Consensus on Meibomian Gland Dysfunction (MGD). Age >=18 years old, <=60 years old; No major systemic diseases; No eye medications have been used in the past three months. There has been no history of eye surgery or trauma in the past six months. Not worn contact lenses in the past six months; Informed consent and signing of written documents.

Exclusion criteria

Exclusion criteria: Combined with other ocular surface lesions or ocular structural abnormalities; Patients with dry eyes secondary to rheumatic immune diseases; There are contraindications for intense pulsed light (OPT) treatment. Taking drugs that may interfere with tear secretion in the past three months; Women who are pregnant or breastfeeding; Those currently participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Non Invasive Tear Break Up Time;

Secondary

MeasureTime frame
Tear meniscus height;Meibomian gland imaging;Chinese Dry Eye Questionnaire Scale;Tear secretion volume;Score for the characteristics of meibomian gland secretions;Expression of various lipids in tears;Positive rate of mites;

Countries

China

Contacts

Public ContactChengcheng Zhu

Qilu Hospital of Shandong University Dezhou Hospital

yankezhuchengcheng@126.com+86 185 0534 2507

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026