Emergence agitation (EA) is a common complication following general anesthesia, characterized by a state of confusion, disorientation, restlessness, crying, or purposeless movements during the recovery period.
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 70 years; 2.ASA physical status I to III; 3.Scheduled for elective oral surgery under general anesthesia with nasotracheal intubation;
Exclusion criteria
Exclusion criteria: 1.Body mass index (BMI) >35 kg/m^²; 2.General anesthesia or sedation within one month prior to surgery; 3.Ischemic heart disease, NYHA >= class III, acute coronary syndrome or stroke within 3 months; 4.Pre-existing neuropsychiatric disorders (e.g., history of schizophrenia, epilepsy, Parkinson's disease, or Alzheimer's disease); 5.Hepatic dysfunction (Child-Pugh C); 6.Renal insufficiency (eGFR 11 mmol/L); 8.Skull base fracture; 9.Previous nasal surgery, severe deviated nasal septum, or recurrent epistaxis;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of recovery at 24 hours postoperatively; | — |
Countries
China
Contacts
Public ContactKePeng
The First Affiliated Hospital of Soochow University
Outcome results
None listed