postoperative pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Scheduled for elective laparoscopy nephrectomy under general anesthesia ; (2) American Society of Anesthesiologists (ASA) physical status class I–III; (3) Age 18–70 years; (4) Body mass index (BMI) < 30 kg/m²; (5) Voluntarily agree to use sufentanil for patient-controlled intravenous analgesia (PCIA) for 24–48 hours; (6) Voluntarily accept the anesthesia protocol and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Contraindications to regional anesthesia (coagulation dysfunction, local infection); (2) Allergy to local anesthetics; (3) Anatomical barriers to regional anesthesia; (4) Severe comorbidities involving vital organs (heart, lung, brain, kidney) or severe systemic diseases; (5) History of chronic pain requiring long-term use of analgesic or sedative medications; (6) Psychiatric disorders or cognitive impairment hindering effective communication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative intravenous morphine equivalent consumption at 24 h; | — |
Secondary
| Measure | Time frame |
|---|---|
| dermatomal coverage of sensory block;blood pressure and heart rate following block;NRS pain scores at 1, 6, 24, and 48 hours postoperatively (both at rest and after activity);time to first patient-controlled analgesia (PCA) demand;rescue analgesia requirement;Quadriceps femoris strength;the incidence of side effects; | — |
Countries
China
Contacts
Beijing Friendship Hospital of Capital Medical University