Psoriasis
Conditions
Interventions
IL-23 Inhibitor Group:NA
IL-17Inhibitor Group:NA
IL-12/23 Inhibitor Group:NA
Sponsors
Zhongshan People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years or older, regardless of gender. 2. Patients who meet the diagnostic criteria: diagnosed with moderate-to-severe plaque psoriasis by physicians in our department based on clinical manifestations and pathological examination, with a baseline Body Surface Area (BSA) of >= 3, Psoriasis Area and Severity Index (PASI) of >= 3, and Dermatology Life Quality Index (DLQI) of >= 6. 3. Patients who voluntarily receive long-term biologic therapy and cooperate with follow-up visits and regular re-examinations.
Exclusion criteria
Exclusion criteria: 1. Presence of severe infections. 2. Allergy to biological agents. 3. Patients with active tuberculosis infection or active hepatitis B virus infection that is untreated. 4. Patients with malignant tumors, autoimmune diseases, or severe systemic diseases (such as cardiovascular, renal, hepatic, or pulmonary diseases) that are either untreated or poorly controlled. 5. History of substance abuse or psychiatric disorders. 6. Women who are pregnant, lactating, or patients with short-term plans for childbearing. 7. Significant abnormalities in laboratory test indicators. 8. Patients who, due to other circumstances, are deemed unsuitable to participate in this study by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dermatology Life Quality Index;Standard Lesion Body Surface Area;Psoriasis Area and Severity Index; | — |
Countries
China
Contacts
Public ContactLi Chen
Zhongshan People’s Hospital
Outcome results
None listed