Seasonal allergic rhinitis
Conditions
Interventions
Gold Standard:specific IgE test,total IgE test
Index test:The diagnostic test under evaluation in this study is the Serum-Stimulated Mast Cell Activation Test. This method simulates the effect of allergens on mast cells in vivo to directly observe
Sponsors
Yulin Hospital, The First Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Case group: (1) Males or females aged 18 to 65 years old; (2) Presenting with typical symptoms clearly attributable to allergies, and the clinical doctor's comprehensive judgment confirms that the symptoms are consistent with the characteristics of an allergic reaction; (3) There is a temporal association between the onset of symptoms and exposure to suspected allergens, with symptoms appearing within a certain period after exposure; (4) Allergen test results meet the following criteria: 1) Weed pollen serum sIgE >= grade II or skin test >= "++"; 2) Dust mite, mold and pet serum sIgE test result 0 grade or skin test result "-". 2.Control group: (1) Males or females aged 18 to 65 years old; (2) Individuals without the above symptoms of allergic rhinitis.
Exclusion criteria
Exclusion criteria: 1. Patients with malignant tumors; 2. Pregnant or breastfeeding individuals; 3. Individuals with other severe liver, kidney, heart, hematopoietic, neurological, or psychiatric diseases; 4. Other situations deemed unsuitable for inclusion by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD63; | — |
Secondary
| Measure | Time frame |
|---|---|
| Histamine; | — |
Countries
China
Contacts
Public ContactWendong Hao
Yulin Hospital, The First Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed