general anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective non-cardiac and non-neurosurgical procedures under general anesthesia, including general surgery, orthopedics, gynecology, neurosurgery, thoracic surgery, hepatobiliary surgery, urology, vascular surgery, and otorhinolaryngology–head and neck surgery; 2. Age between 18 and 85 years; 3. ASA physical status classification I–IV; 4. Expected surgery duration >= 60 minutes.
Exclusion criteria
Exclusion criteria: 1. Patients with diseases affecting EEG acquisition, such as poisoning, epilepsy or related syndromes, central nervous system infection, ischemic or hypoxic encephalopathy, neurodegenerative disorders (including Alzheimer’s disease, Lewy body dementia, Parkinson’s disease, Huntington’s disease), or cortical dysplasia; 2. Patients undergoing burn surgery, organ transplantation, cesarean section, or emergency operations; 3. Patients who refuse to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BIS (Bispectral Index);TOF (train-of-four);NoL (nociception level);HRV (Heart rate variability);Drug plasma concentration;GOF (goodness-of-fit);pcVPC (prediction-corrected visual predictive check); | — |
Countries
China
Contacts
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College