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Clinical efficacy study on accelerating repetitive transcranial magnetic stimulation for treating adolescent depression

Clinical efficacy study on accelerating repetitive transcranial magnetic stimulation for treating adolescent depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113943
Enrollment
Unknown
Registered
2025-12-04
Start date
2025-12-07
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Intervention group:Using figure-eight stimulation coils, with 80% of the resting motor threshold as the stimulation intensity, 1,200 inhibitory pulses were applied to the right dorsolateral prefrontal

Sponsors

Shandong Daizhuang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 19 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 10 and 19 years old; 2. Diagnosis of depression confirmed by the Structured Clinical Interview for DSM-5 (SCID-V); 3. Diagnosis of depression accompanied by anxiety symptoms (HAMD total score = 24 and HAMA total score = 18); 4. Right-handed; 5. No changes in treatment regimen for 4 weeks prior to enrollment and throughout the treatment period; 6. Capable of complying with and completing the trial protocol.

Exclusion criteria

Exclusion criteria: 1. History of substance dependence (including alcohol or drug dependence); 2. Presence or history of other psychiatric disorders meeting SCID Axis I diagnostic criteria; 3. Contraindications to rTMS treatment; 4. Personal or family history of epilepsy; 5. Pregnancy or lactation; 6. Systematic physical therapy (e.g., electroconvulsive therapy, transcranial direct current stimulation, etc.) within the past six months; 7. Current or previous traumatic brain injury or other known organic lesions of the central nervous system.

Design outcomes

Primary

MeasureTime frame
The effects of accelerated repetitive transcranial magnetic stimulation on improving depressive symptoms (HAMD-24) and anxiety (HAMA) in patients with depression;

Countries

China

Contacts

Public ContactKun Li

Shandong Daizhuang Hospital

likunyjs@163.com+86 195 5370 0077

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026