None
Conditions
Interventions
Remimazolam group:Remimazolam
Propofol group:Propofol
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age = 60 years, regardless of gender; 2.Patients scheduled to undergo non-cardiovascular surgery (elective/emergency) under general anesthesia, with an operation time > 0.5 hours and = 4 hours; 3.ASA classification grades I to III; 4.Conforming to ethics, without dementia, and the patients voluntarily participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Any cerebrovascular accident occurring within 3 months, such as stroke, transient ischemic attack (TIA), etc. 2.Those who have experienced unstable angina pectoris or myocardial infarction within 3 months; 3.Severe valvular heart disease, atrial fibrillation, frequent atrial premature beats or ventricular premature beats, congestive heart failure, etc.; 4.Preoperative visit blood pressure = 180/110 mm Hg (grade 3 hypertension according to the WHO-ISH hypertension guidelines); 5.Those with confirmed or suspected abuse of or long-term use of narcotic sedative analgesics; 6.Those with a history of asthma; 7.Patients with a preoperative MMSE score of < 18 points; 8.Perioperative sudden severe complications; 9.Termination of the clinical protocol for any reason or withdrawal at the patient's request;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of In-Hospital Postoperative Complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic stability during anesthesia; | — |
Countries
China
Contacts
Public ContactWang Yong
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed