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The predictive value of the APOA-1/HDL ratio for the severity and clinical outcomes of patients with severe community-acquired pneumonia: A single-center prospective observational study

The predictive value of the APOA-1/HDL ratio for the severity and clinical outcomes of patients with severe community-acquired pneumonia: A single-center prospective observational study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113937
Enrollment
Unknown
Registered
2025-12-04
Start date
2025-12-05
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community-acquired pneumonia, cough with expectoration, fever

Interventions

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age >=18 years old; 2. Conforming to the diagnostic criteria of SCAP in the 2007 ATS/IDSA guidelines; 3. Obtain informed consent;

Exclusion criteria

Exclusion criteria: 1. Those who have been bedridden for a long time before admission and have severe immune deficiencies (such as HIV/AIDS, long-term use of high-dose hormones/immunosuppressants after organ transplantation) ; 2. End-stage liver disease (Child-Pugh grade C) or end-stage renal disease (regular dialysis); 3. Active malignant tumors that are currently undergoing chemotherapy or radiotherapy; 4. Before admission, the patient was diagnosed with abnormal lipid metabolism and is currently receiving relevant treatment; 5.Those with an expected survival time of less than 24 hours or who give up active treatment within 24 hours after admission; 6. Women and lactating women; 7. Unable to obtain informed consent.

Design outcomes

Secondary

MeasureTime frame
Length of stay in the ICU;Mechanical ventilation time;

Primary

MeasureTime frame
28-day all-cause mortality;

Countries

China

Contacts

Public ContactWei Dongpo

Shanghai General Hospital

420493303@qq.com+86 21 6324 0090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026