Glaucoma is a group of diseases with characteristic optic atrophy and visual field defect, and pathological increase of intraocular pressure is the main risk factor. Primary glaucoma is a kind of glaucoma whose etiological mechanism is not fully understood. According to the state of the anterior chamber Angle when the intraocular pressure rises - closed or open, it can be divided into angle-closed
Conditions
Interventions
Control group:None
Case group:None
Sponsors
Army Characteristic Medical Center, Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for the case group: (1) Age >=55 years; (2) Patients diagnosed with primary glaucoma based on the 2014 Expert Consensus on the Diagnosis and Treatment of Primary Glaucoma in China by the Glaucoma Subgroup of the Chinese Ophthalmological Society, meeting at least four of the following criteria: 1) Intraocular pressure (IOP) >=21 mmHg; 2) Cup-to-disc ratio (CDR) >=0.6 or interocular CDR difference >0.2; 3) RNFL defect; 4) Early visual field loss; (3) Uncorrected or best-corrected visual acuity >0.3, refractive error 0.3, refractive error <=+/-6D; (3) No history of major diseases or infectious diseases (including Hepatitis B, Hepatitis C, HIV, Syphilis); (4) Scheduled for cataract surgery and meeting surgical indications; (5) Voluntary participation in the study with signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cognitive decline or inability to cooperate with examinations; 2. Patients with other vitreous or retinal diseases (including hereditary vitreoretinal degeneration, vitreous opacities, retinal vascular occlusion, arteriosclerosis, hematologic retinopathy, diabetic retinopathy, epiretinal membrane, retinal degeneration, and retinal dystrophy); 3. Patients with a history of intraocular surgery, including glaucoma surgery and non-glaucoma intraocular surgery; 4. Patients with ocular perforating or blunt trauma caused by intraocular foreign bodies, or secondary angle abnormalities or secondary glaucoma resulting from intraocular foreign bodies; 5. Patients with other neurodegenerative diseases or comorbidities that interfere with spinal cord assessment, such as multiple sclerosis, amyotrophic lateral sclerosis, vitamin B12 deficiency, and progressive spastic paraparesis (including hereditary spastic paraparesis); 6. Patients who have not provided informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of Mini-mental state examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Eyesight;Visual field;Results of photopic negative response(PhNR);Intraocular pressure;OCT outcome;Basic demographic and clinical characteristics of participants (name, gender, age, time of glaucoma diagnosis, type of glaucoma, etc.); | — |
Countries
China
Contacts
Public ContactLiu,Ting
Army Characteristic Medical Center, Chinese People's Liberation Army
Outcome results
None listed