Perioperative neurocognitive disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.a) Patients undergoing elective major surgery (colorectal, pancreatic-gastric, hepatobiliary, thoracic, gynaecological and urological) under general anaesthesia; 2.b) Expected duration of surgery >2 hours; 3.c) Age>=65 years; 4.d) Expected duration of postoperative hospital stay>=7 days;
Exclusion criteria
Exclusion criteria: 1.a) refused to participate in this study; 2.b) preoperative MMSE score 9); 3.c) underwent neurosurgery or the surgery itself interfered with the patient's postoperative communicative communication (e.g., tracheotomy); 4.d) severe organ dysfunction; 5.and e) underwent cardiac surgery, (e) Undergoing cardiac surgery, neurosurgery, or neurosurgery; 6.(f) ASA classification IV or higher. Translated with DeepL.com (free version);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of DNR within 30 days postoperatively;;Non-delirium complications within 30 days postoperatively;;Postoperative hospital stay and medical expenses during hospitalization;;Measurement results of brain function status in PND patients;;Mortality rate within 30 days postoperatively.; | — |
Countries
China
Contacts
Cancer Hospital Chinese Academy of Medical Sciences