A patient under general anesthesia
Conditions
Interventions
Experimental group:Patients in the experimental group received a slow intravenous infusion of 1 mg of tigeseridine 10 minutes before the end of surgery for postoperative analgesia. Anesthesia was indu
Control group:Patients in the control group received a slow intravenous infusion of 0.05 mg fentanyl 10 minutes before the end of surgery for postoperative analgesia. Anesthesia was induced with propo
Sponsors
Suzhou Ninth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years; 2. Anesthesia Society of America (ASA) grade I to II; 3. Body mass index (BMI) between 18 and 30 kg/m^2; 4. Patients scheduled for laparoscopic cholecystectomy; 5. Provision of signed informed consent preoperatively, with demonstrated ability to comprehend and comply with study procedures.
Exclusion criteria
Exclusion criteria: 1. Patients allergic to opioid drugs or any component of the investigational drug; 2. Patients with a history of long-term use or abuse of opioid drugs; 3. Patients combined with severe cardiac, hepatic, or renal dysfunction or neuropsychiatric diseases; 4. Pregnant or lactating women; 5. Patients with a history of PONV or severe motion sickness; 6. Patients deemed ineligible for enrollment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sum of Pain Intensity Differences over 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting Numeric Rating Scale;Dosage of Opioid;Nausea;Vomiting;Adverse reaction incidence;Quality of Recovery-15; | — |
Countries
China
Contacts
Public ContactChao Zhang
Suzhou Ninth People's Hospital
Outcome results
None listed